The APPIC trial focusses on investigating the efficacy and safety of a restrictive course of antibiotics after appendectomy for complex acute appendicitis. This website offers information for both patient and professional.

On June 9th 2017 the first patient was included into the APPIC trial. Throughout the Netherlands 15 hospitals participate in the trial. The aim is to include 1066 patients in total by the end of 2020. Due to the corona-situation the inclusion of patients is temporarily on-hold in 6 participating hospitals.

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